Ryan Notti, MD, PhD, is an Instructor in Clinical Investigation at the Rockefeller University and Special Fellow in the Department of Medicine at Memorial Sloan Kettering Cancer Center. He works in the Laboratory of Molecular Electron Microscopy at Rockefeller, headed by Professor Thomas Walz, PhD, where they are working to expand our structural understanding of immune signaling. Specifically, he is dissecting the structural mechanics of T-cell receptor activation, with the aim of engineering improved cancer immunotherapies.

Dr. Notti received his BS from the University of Connecticut (Honors) in the Biological Sciences. He completed MD-PhD training in the Tri-Institutional Medical Scientist Training Program, receiving his MD from Weill Cornell Medical College and his PhD from The Rockefeller University where he studied the structural biology of type III secretion system assembly with Dr. C. Erec Stebbins. He completed his Internship and Residency in Internal Medicine at NewYork-Presbyterian Hospital (Cornell) and his Fellowship in Medical Oncology at Memorial Sloan Kettering Cancer Center with Dr. William Tap on the Sarcoma Medical Oncology Service, where he was also Chief Fellow. He is currently a scholar in the Rockefeller University KL2 Clinical Scholars Program, where he serves as Chief Scholar.
Instructor in Clinical Investigation